Estradiol valerate and estradiol valerate/dienogest (natazia) tablets: the first four-phasic oral contraceptive.
نویسندگان
چکیده
614 P&T® • November 2010 • Vol. 35 No. 1
منابع مشابه
Natazia®: a New Combination Oral Contraceptive
JALYN® (DUTASTERIDE/TAMSULOSIN): A NEW OPTION IN BPH n the U.S., the leading method of contraception is the combination oral contraceptive pill. More than 10 million women aged 15-44 years use the birth control pill as their primary method of contraception.1 Since the first BCP approval in 1960, the FDA has approved many oral contraceptive products. Most of these products use ethinyl estradiol ...
متن کاملReview of the safety, efficacy and patient acceptability of the combined dienogest/estradiol valerate contraceptive pill
The aim of this review is to define the role of the combined dienogest (DNG)/estradiol valerate (E2V) contraceptive pill, in terms of biochemistry, metabolic and pharmacological effects and clinical application as well. E2V is the esterified form of 17β-estradiol (E2), while dienogest is a fourth-generation progestin with a partial antiandrogenic effect. The cycle stability is achieved with 2 t...
متن کاملEstradiol valerate and dienogest: a new approach to oral contraception
Most combination oral contraceptives contain ethinyl estradiol and a progestin. A new and novel oral contraceptive formulation combines estradiol valerate (E2V) with dienogest (DNG) in a four-phase dosing regimen. 17β-estradiol is a naturally-occurring estrogen, and a contraceptive pill containing such an estrogen offers potential benefits with regard to metabolic side effects and adverse event...
متن کاملAn overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest
Natural estrogens such as estradiol (E(2)) or its valerate ester (E(2)V) offer an alternative to ethinyl estradiol (EE). E(2)-containing combined oral contraceptives (COCs) have demonstrated sufficient ovulation inhibition and acceptable contraceptive efficacy. However, earlier formulations were generally associated with unacceptable bleeding profiles. Two E(2)V-containing preparations have bee...
متن کاملHemostatic Effects of a Novel Estradiol-Based Oral Contraceptive
BACKGROUND A novel estradiol-based combined oral contraceptive (COC) is currently available in many countries worldwide, including Europe and the US. Based on previous studies, it is expected that this estradiol-based COC will have a reduced hepatic effect compared with COCs containing ethinylestradiol with regard to proteins controlling the hemostatic balance. OBJECTIVE The aim of this study...
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ورودعنوان ژورنال:
- P & T : a peer-reviewed journal for formulary management
دوره 35 11 شماره
صفحات -
تاریخ انتشار 2010